High-Performance Chromatography Equipment for Cannabis and Hemp Processing
Unlock the power of advanced chromatography with Root Sciences. Our cutting-edge chromatography equipment is designed for precise compound separation, making it the ideal solution for THC remediation, purification, and quality refinement. As industry leaders, we provide high-performance systems that ensure efficiency, reliability, and scalability—helping you achieve superior product purity with confidence. Explore our chromatography offerings and take your extraction process to the next level
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Cannabis Chromatography Equipment Offerings
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HPLC (High-Performance Liquid Chromatography) Equipment
MetaPür’s HPLC systems provide a complete purification solution, supporting both bench and process scale operations. Designed to handle a range of pressure requirements, these systems accommodate column media from 10 to 50 μm, ensuring flexibility for various purification needs, including reverse phase, normal phase, ion exchange, and chiral separations. Key features include pulse-free flow paths, multi-column and stacked injection capabilities, and advanced UV diode array detection. With automated clean-in-place (CIP), remote control, and full compliance with 21CFR Part 11, cGMP, GLP, and FDA regulations, MetaPür’s systems are engineered for optimum efficiency and reliability in your THC remediation processes.
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Column Chromatography
MetaPür’s axial compression columns are designed for precision and efficiency across analytical, pilot, and process scale chromatography. Offering a full range of sizes, these columns are engineered for rapid unpacking and repacking, with a 20 cm ID column requiring less than an hour. A proprietary set of channels in the end fittings ensures uniform flow distribution across the column bed, resulting in enhanced performance by increasing the number of theoretical plates and minimizing peak broadening. This optimal flow distribution delivers improved peak shape and height, translating to higher purity and yield for your THC remediation processes.
Chromatography is an advanced purification technique used in cannabis extraction to separate and isolate specific compounds such as THC, CBD, minor cannabinoids, and terpenes. This process relies on a solvent-based method to fractionate cannabis extracts, allowing manufacturers to achieve high-purity distillates and compliant cannabinoid formulations. By precisely removing unwanted substances, such as lipids, chlorophyll, and residual solvents, chromatography ensures a cleaner, more potent final product. This technology is essential for producing pharmaceutical-grade cannabis extracts, creating full-spectrum and isolate formulations that meet regulatory standards and consumer demands.
- Preparation: Cannabis crude oil or extracted material is dissolved in a solvent system, preparing it for precise compound separation.
- Separation Process: The extract is passed through a chromatography column filled with a stationary phase, where cannabinoids are separated based on their molecular interactions, polarity, and weight.
- Purification: Specific compounds—like THC, CBD, and minor cannabinoids—are selectively collected, while impurities, pigments, and unwanted substances are removed.
- Final Product: The end result is an isolated, high-purity cannabinoid fraction, ready for formulation into pharmaceutical, nutraceutical, or consumer products.
- High Precision in Compound Separation – Achieves unmatched accuracy in cannabinoid isolation.
- Superior Purity and Potency – Produces pharmaceutical-grade THC, CBD, and minor cannabinoid extracts.
- Efficient Isolation of Cannabinoids – Separates full-spectrum, broad-spectrum, and isolate formulations.
- Compliance with Health and Safety Standards – Ensures THC remediation to meet regulatory limits.
- Scalable Solutions for Different Production Needs – Suitable for both lab-scale and high-volume manufacturing.
- User-Friendly Operation and Maintenance – Designed for automated control and simplified workflows.
Choosing the ideal cannabis chromatography equipment depends on several key factors:
- Scale of Production – From research labs to industrial-scale processing.
- Compound Isolation Requirements – Custom solutions for THC, CBD, CBG, and rare cannabinoids.
- Solvent Use and Recovery – Optimized solvent recycling for cost savings and efficiency.
- Automation and Control Features – Advanced PLC automation for precise separation.
- Compliance and Certifications – Designed to meet GMP, FDA, and state cannabis regulations.
- Cost-Effectiveness – Considerations for return on investment, scalability, and operational efficiency.
- Future-Proofing Features – Adaptable technology to meet evolving industry demands.
1. What compounds can be isolated with your chromatography system?
Our chromatography solutions can isolate THC, CBD, CBG, CBC, CBN, and other minor cannabinoids, as well as remove unwanted contaminants.
2. How does chromatography differ from other purification methods?
Unlike distillation or winterization, chromatography offers precise compound separation, ensuring compliance with THC limits and producing pharmaceutical-grade purity.
3. What solvents are used, and how are they recovered?
Our systems use industry-standard solvents like ethanol, heptane, or pentane, with built-in solvent recovery systems for cost-effective operation.
4. What are the benefits of using chromatography in cannabis extraction?
Chromatography ensures THC remediation, high cannabinoid purity, efficient separation, and regulatory compliance—ideal for medical, edible, and vape formulations.
5. How do I select the right chromatography system for my production scale?
Our experts can guide you in choosing between lab-scale, pilot, or industrial chromatography systems, ensuring efficiency and maximized yield.
6. Can chromatography be used to comply with regulatory THC limits?
Yes. Our chromatography systems are ideal for THC remediation, allowing manufacturers to create compliant broad-spectrum or THC-free extracts.
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